僅用于工業應用或科學研究，不可用于人類或動物的臨床診斷或治療，非藥用. Letolizumab （BMS-986004） is a monoclonal antibody targeting CD40L, which is produced to express mutant IgG1 lacking effector function, including Fc binding and complement fixation. Letolizumab reduces rejection, thromboembolism and prolongs the survival time